Learning From the Transgenic Mouse

Learning from the transgenic mouse: endothelium, adhesive molecules, and neointimal formation.

Vascular remodeling plays an important role in the development of native atherosclerosis and restenosis after PTCA. A typical atherosclerotic plaque consists of a core of lipid-rich macrophages surrounded by a thickened intima under the cover of a fibrous cap. Endothelial cell injury, related to shear forces and modified by certain risk factors, appears to be a critical initial event in atherog...

exploring senior high-school iranian students’ dominant learning style preferences in learning english: how are “good language learners” different from the majority?

چکیده بسیاری از محققان جنبه های مختلفی از سبک های یادگیری را مورد بررسی قرار داده اند. با این وجود، مطالعات بسیار کمی تعاملات بین مفاهیم سبک های یادگیری و " زبان آموزان خوب" " را در مورد توجه قرار داده است. بدین دلیل، هدف کلی این مطالعه بررسی ترجیحات سبکهای یادگیری غالب در دانش آموزان دبیرستانی ایران، و مقایسه آن با ترجیحات سبکهای یادگیری غالب " زبان آموزان خوب" می باشد. با این هدف ، پرسشنامه ...

Connexin diversity in the heart: insights from transgenic mouse models

Cardiac conduction is mediated by gap junction channels that are formed by connexin (Cx) protein subunits. The connexin family of proteins consists of more than 20 members varying in their biophysical properties and ability to combine with other connexins into heteromeric gap junction channels. The mammalian heart shows regional differences both in connexin expression profile and in degree of e...

Can We Trust the Transgenic Mouse? Insights from Computer Simulations

Over the past several decades, the mouse has gained prominence in the cardiac electrophysiology literature as the animal model of choice. Using computer models of the mouse and human ECG, this paper is a step toward understandingwhen themouse succeeds and fails tomimic functional changes resulting from disease states and drug interactions.

New insight on immune tolerance from transgenic mouse models.